Cross reactivity carboplatin cisplatin
WebJan 11, 2009 · Carboplatin is a weaker analog of cisplatin. Carboplatin doesn't cross-link DNA as efficiently as cisplatin, and because of this, its side effects are not as pronounced. The potential risk of developing a secondary are … WebHypersensitivity and cross-reactivity to cisplatin and analogues. We report on a 49-year-old woman with relapsing ovarian cancer who developed a hypersensitivity reaction (HSR) to …
Cross reactivity carboplatin cisplatin
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WebFeb 1, 2024 · Finally, cross-reactivity between carboplatin and oxaliplatin has been estimated to be between 37-45%, being much lower with cisplatin [34]. ... Management of hypersensitivity reactions... WebJun 1, 2016 · Carboplatin, a second-generation platinum antitumor drug and a derivative of cisplatin with good chemical stability, higher tolerance and less side effects compared with cisplatin, is mainly used...
WebSep 1, 2013 · Cross-reactivity among carboplatin, oxaliplatin, and cisplatin was also assessed by adding cisplatin sIgE to the in vitro evaluation panel. Methods The present …
WebOct 14, 2024 · Cisplatin is a chemotherapy drug useful in treating testicular, ovarian, bladder, head and neck, lung, and cervical cancer. This compound is the prototype … WebHypersensitivity reactions(HSRs) are a subset of IRs that occur at doses normally tolerated by patients and are not consistent with a known toxicity of the drug.2HSRs can be divided into subtypes as defined by Gell and Coombs, depending on the mechanism of reaction.
Webcisplatin, and its toxicity profile is more favorable. Here we report on a 50-year-old woman with a history of cervix cancer who developed a severe hypersensitivity reaction (HSR) …
WebJan 19, 2024 · Carboplatin hypersensitivity: a 6-h 12-step protocol effective in 35 desensitizations in patients with gynecological malignancies and mast cell/IgE-mediated … images treasurerWebAug 2, 2024 · Carboplatin and cisplatin are commonly used for ovarian, lung, and head and neck cancers (Table 1) . Carboplatin-based regimens are frequently recommended … list of country singers from the 80s and 90sWebThere is a low rate of cross-reactivity between cisplatin and other platins such as carboplatin and oxaliplatin. A recent study evaluated 43 patients with histories of allergic … list of country singers femaleWebOct 5, 2014 · Unlike cisplatin, carboplatin may be susceptible to alternative mechanisms. Some studies show that cisplatin and carboplatin cause different morphological changes in MCF-7 cell lines while exerting their cytotoxic behavior (Natarajan, Malathi et al., 1999). The diminished reactivity limits protein-carboplatin complexes, which are excreted. images tree frogsWebA 49-year-old woman with relapsing ovarian cancer who developed a hypersensitivity reaction (HSR) to carboplatin and, subsequently, to cisplatin may prevent a small population of young patients from receiving effective therapy with cis platin or its analogues. We report on a 49-year-old woman with relapsing ovarian cancer who developed a … images treasure island flWebCisplatin and carboplatin may play an important role in the antitumor immune response, which could impact the outcome of subsequent pembrolizumab treatment. Given that the rate of response to pembrolizumab after dose-reduced GC chemotherapy was relatively low, this regimen is not recommended for cis … images treasure chestWebFor carboplatin and cisplatin, the first hypersensitivity reaction typically occurs around the second and third re-exposure during the second line of therapy (eighth and ninth courses … images tree stump art